Preclinical In-Vitro Toxicology Scientist

United Kingdom Hudson Shribman Preclinical In-Vitro Toxicology Scientist up to c£70k + Bonus + Benefits Hampshire, Full Time ABJ6761 ONSITE - Hybrid – PERM An exciting opportunity has arisen for an experienced In-Vitro Regulatory Toxicology Scientist to join a leading scientific research and product development organisation focused on in-vitro and pre-clinical assessment. This is an excellent opportunity for an experienced scientist to take a technically influential role within a multidisciplinary environment, contributing to advanced pre-clinical testing capabilities across in-vitro science, product development and regulatory toxicology. You will provide technical expertise and scientific direction across in-vitro Regulatory and Genetic Toxicology, supporting pre-clinical research, product development and regulatory programmes. The role will suit an experienced toxicologist with strong hands-on laboratory expertise who can work independently, lead technical activities and collaborate with internal teams and external partners. Key Responsibilities * Provide technical expertise in the development and application of in-vitro Regulatory Toxicology approaches. * Lead and execute in-vitro studies, delivering robust, reliable and scientifically defensible data. * Develop, optimise and apply Neutral Red, Ames and in-vitro micronucleus assays. * Apply complex cell culture, exposure techniques and biological testing methodologies to investigate product safety and potential human health effects. * Interpret experimental findings and bridge in-vitro data with analytical, human-use and clinical information where appropriate. * Provide technical direction for new testing capabilities, methodologies and assessment strategies. * Plan and deliver technical work programmes to agreed timescales, quality standards and objectives. * Collaborate with multidisciplinary teams across Preclinical Science, Analytical Science, Toxicology, Clinical and Product Development. * Build relationships with external technical partners, CROs, academic groups and specialist consultants. * Support method transfer, validation and implementation of new technologies. * Ensure data is generated and managed in line with appropriate quality and regulatory requirements within controlled, quality-assured laboratory environments. * Contribute to continuous improvement of laboratory methods, processes and scientific capabilities. * Prepare, author and peer-review scientific reports, technical documentation, regulatory materials, presentations and publications. * Support external scientific collaborations, including method transfer and inter-laboratory validation. Experience & Skills Required * Degree, MSc or PhD in Biological Sciences, Toxicology, Pharmacology, Biomedical Sciences, Cell Biology, Molecular Biology or a related discipline. * Significant practical experience in in-vitro Regulatory Toxicology, Genetic Toxicology or pre-clinical area. * Hands-on experience with Neutral Red, Ames and/or in-vitro micronucleus testing. * Strong experience in complex cell culture, exposure techniques, biological assays and data interpretation. * Experience developing, optimising, transferring or validating in-vitro testing methodologies. * Understanding of relevant regulatory toxicology guidelines, including OECD, ECVAM and ICCVAM. * Experience within a controlled, quality-assured laboratory environment, ideally with GMP, GLP or GxP. * Ability to assess complex biological datasets using appropriate data analysis, computational or bioinformatics. * Experience contributing to regulatory submissions, scientific reports, technical documentation or external scientific communications. Desirable * Experience in disease modelling, molecular toxicology or adverse outcome pathway frameworks. * Knowledge of bioinformatics, computational biology or advanced biological data analysis. * Experience with high-content screening, high-throughput assays or innovative in-vitro platforms. * Experience managing CROs, suppliers or scientific collaborations. Benefits: Up to £70k + up to 30% bonus + 20% pension To Apply: Please contact Alison Basson on (phone number removed) / (phone number removed) or apply quoting ABJ6761 to